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Phospholamban 抗体 (N-Term)

PLN 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3043442
发货至: 中国
  • 抗原 See all Phospholamban (PLN) 抗体
    Phospholamban (PLN)
    抗原表位
    • 30
    • 18
    • 16
    • 9
    • 7
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-35, N-Term
    适用
    • 83
    • 23
    • 22
    • 3
    • 2
    • 2
    • 2
    人, 大鼠, 小鼠
    宿主
    • 83
    • 1
    • 1
    克隆类型
    • 83
    • 2
    多克隆
    标记
    • 32
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This Phospholamban antibody is un-conjugated
    应用范围
    • 32
    • 26
    • 26
    • 25
    • 13
    • 10
    • 9
    • 8
    • 7
    • 6
    • 6
    • 4
    • 1
    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for Cardiac phospholamban(PLN) detection. Tested with WB in Human,Mouse,Rat.
    序列
    MEKVQYLTRS AIRRASTIEM PQQARQKLQN LFINF
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Cardiac phospholamban(PLN) detection. Tested with WB in Human,Mouse,Rat.
    Gene Name: phospholamban
    Protein Name: Cardiac phospholamban
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the N-terminus of human PLN(1-35aa MEKVQYLTRSAIRRASTIEMPQQARQKLQNLFINF), different from the related mouse and rat sequences by one amino acid.
    亚型
    IgG
    Top Product
    Discover our top product PLN Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat, The detection limit for PLN is approximately 0.1 ng/lane under reducing conditions.
    Notes: Tested Species: Species with positive results.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    Phospholamban (PLN)
    别名
    PLN (PLN 产品)
    别名
    LOC100226261 antibody, plb antibody, cmd1p antibody, CMD1P antibody, CMH18 antibody, PLB antibody, Plb antibody, Plm antibody, phospholamban antibody, PLN antibody, pln antibody, Pln antibody
    背景
    Phospholamban is a 52 amino acid integral membrane protein that regulates the Ca2+ pump in cardiac muscle and skeletal muscle cells. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic response elicited in heart by beta-agonists. Phospholamban is also expressed in slow-twitch skeletal muscle and some smooth muscle cells. It is observed that human ventricle and quadriceps displayed high levels of phospholamban transcripts and proteins, with markedly lower expression observed in smooth muscles, while the right atrium also expressed low levels of phospholamban. The structure of the human phospholamban gene closely resembles that reported for chicken, rabbit, rat, and mouse. Comparison of the human to other mammalian phospholamban genes indicated a marked conservation of sequence for at least 217 bp upstream of the transcription start site.

    Synonyms: Cardiac phospholamban antibody|CMD1P antibody|CMH18 antibody|PLB antibody|PLN antibody|PPLA_HUMAN antibody
    基因ID
    5350
    UniProt
    P26678
    途径
    Negative Regulation of Transporter Activity
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