PGAM5 抗体 (AA 30-225)
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北京 101111
Quick Overview for PGAM5 抗体 (AA 30-225) (ABIN7269317)
抗原
See all PGAM5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 30-225
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原理
- PGAM5 Rabbit pAb
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序列
- KPRAGGDAEP RPAEPPAWAG GARPGPGVWD PNWDRREPLS LINVRKRNVE SGEEELASKL DHYKAKATRH IFLIRHSQYH VDGSLEKDRT LTPLGREQAE LTGLRLASLG LKFNKIVHSS MTRAIETTDI ISRHLPGVCK VSTDLLREGA PIEPDPPVSH WKPEAVQYYE DGARIEAAFR NYIHRADARQ EEDSYE
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 30-225 of human PGAM5 (NP_612642.2).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- PGAM5 (Phosphoglycerate Mutase Family Member 5 (PGAM5))
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别名
- PGAM5
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背景
- Displays phosphatase activity for serine/threonine residues, and, dephosphorylates and activates MAP3K5 kinase. Has apparently no phosphoglycerate mutase activity. May be regulator of mitochondrial dynamics. Substrate for a KEAP1-dependent ubiquitin ligase complex. Contributes to the repression of NFE2L2-dependent gene expression. Acts as a central mediator for programmed necrosis induced by TNF, by reactive oxygen species and by calcium ionophore.,PGAM5,BXLBV68,Signal Transduction,PGAM5
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分子量
- 28kDa/32kDa
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基因ID
- 192111
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UniProt
- Q96HS1
抗原
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