PDE12 抗体 (AA 17-300)
Quick Overview for PDE12 抗体 (AA 17-300) (ABIN7269299)
抗原
See all PDE12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 17-300
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原理
- PDE12 Rabbit pAb
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序列
- AVEKLSRAEA GSQTAAGAME RAVVRCVPSE PKLSLSFALA DGSHKNMQRD QSEPLGRVLS RIATNALKGH AKAAAAKKSR KSRPNASGGA ACSGPGPEPA VFCEPVVKLY YREEAVAEDV LNVDAWQDGA VLQIGDVKYK VERNPPAFTE LQLPRYIMAG FPVCPKLSLE FGDPASSLFR WYKEAKPGAA EPEVGVPSSL SPSSPSSSWT ETDVEERVYT PSNADIGLRL KLHCTPGDGQ RFGHSRELES VCVVEAGPGT CTFDHRHLYT KKVTEDALIR TVSY
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交叉反应
- 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 17-300 of human PDE12 (NP_001309106.1).
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亚型
- IgG
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anti-Phosphodiesterase 12 (PDE12) (AA 1-575) antibody
PDE12 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Phosphodiesterase 12 (PDE12) (C-Term) antibodyPDE12 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 犬, 兔, 猴, Pig, Bat, 小鸡, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Phosphodiesterase 12 (PDE12) (AA 290-602) antibodyPDE12 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Phosphodiesterase 12 (PDE12) (AA 362-390), (C-Term) antibodyPDE12 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB27765 unconjugated
anti-Phosphodiesterase 12 (PDE12) (AA 369-398), (C-Term) antibodyPDE12 适用: 人 WB, FACS, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- PDE12 (Phosphodiesterase 12 (PDE12))
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别名
- PDE12
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背景
- Enzyme that cleaves 2',5'-phosphodiester bond linking adenosines of the 5'-triphosphorylated oligoadenylates, triphosphorylated oligoadenylates referred as 2-5A modulates the 2-5A system. Degrades triphosphorylated 2-5A to produce AMP and ATP. Also cleaves 3',5'-phosphodiester bond of oligoadenylates. Plays a role as a negative regulator of the 2-5A system that is one of the major pathways for antiviral and antitumor functions induced by interferons (IFNs. Suppression of this enzyme increases cellular 2-5A levels and decreases viral replication in cultured small-airway epithelial cells and Hela cells.,PDE12,2-PDE,PDE12
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基因ID
- 201626
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UniProt
- Q6L8Q7
抗原
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