PDE11A 抗体 (AA 712-933)
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北京 101111
Quick Overview for PDE11A 抗体 (AA 712-933) (ABIN7269298)
抗原
See all PDE11A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 712-933
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原理
- PDE11A Rabbit pAb
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序列
- NNAFQAKSGS ALAQLYGTSA TLEHHHFNHA VMILQSEGHN IFANLSSKEY SDLMQLLKQS ILATDLTLYF ERRTEFFELV SKGEYDWNIK NHRDIFRSML MTACDLGAVT KPWEISRQVA ELVTSEFFEQ GDRERLELKL TPSAIFDRNR KDELPRLQLE WIDSICMPLY QALVKVNVKL KPMLDSVATN RSKWEELHQK RLLASTASSS PASVMVAKED RN
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交叉反应
- 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 712-933 of human PDE11A (NP_058649.3).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- PDE11A (phosphodiesterase 11A (PDE11A))
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别名
- PDE11A
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背景
- The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene.,PDE11A;PPNAD2,PDE11A
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分子量
- 55kDa/65kDa/78kDa/104kDa
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基因ID
- 50940
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UniProt
- Q9HCR9
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途径
- cAMP Metabolic Process
抗原
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