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PDE11A 抗体 (AA 712-933)

This anti-PDE11A antibody is a 兔 多克隆 antibody detecting PDE11A in WB 和 IF. Suitable for 人.
产品编号 ABIN7269298
发货至: 中国

Quick Overview for PDE11A 抗体 (AA 712-933) (ABIN7269298)

抗原

See all PDE11A 抗体
PDE11A (phosphodiesterase 11A (PDE11A))

适用

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宿主

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克隆类型

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多克隆

标记

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This PDE11A antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

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    AA 712-933

    原理

    PDE11A Rabbit pAb

    序列

    NNAFQAKSGS ALAQLYGTSA TLEHHHFNHA VMILQSEGHN IFANLSSKEY SDLMQLLKQS ILATDLTLYF ERRTEFFELV SKGEYDWNIK NHRDIFRSML MTACDLGAVT KPWEISRQVA ELVTSEFFEQ GDRERLELKL TPSAIFDRNR KDELPRLQLE WIDSICMPLY QALVKVNVKL KPMLDSVATN RSKWEELHQK RLLASTASSS PASVMVAKED RN

    交叉反应

    小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 712-933 of human PDE11A (NP_058649.3).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    PDE11A (phosphodiesterase 11A (PDE11A))

    别名

    PDE11A

    背景

    The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene.,PDE11A;PPNAD2,PDE11A

    分子量

    55kDa/65kDa/78kDa/104kDa

    基因ID

    50940

    UniProt

    Q9HCR9

    途径

    cAMP Metabolic Process
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