NLRP12 抗体 (AA 862-1062)
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Quick Overview for NLRP12 抗体 (AA 862-1062) (ABIN7268937)
抗原
See all NLRP12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 862-1062
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原理
- NLRP12 Rabbit pAb
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序列
- LWLKICRLTA AACDELASTL SVNQSLRELD LSLNELGDLG VLLLCEGLRH PTCKLQTLRL GICRLGSAAC EGLSVVLQAN HNLRELDLSF NDLGDWGLWL LAEGLQHPAC RLQKLWLDSC GLTAKACENL YFTLGINQTL TDLYLTNNAL GDTGVRLLCK RLSHPGCKLR VLWLFGMDLN KMTHSRLAAL RVTKPYLDIG C
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交叉反应
- 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 862-1062 of human NLRP12 (NP_001264055.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))
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别名
- NLRP12
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背景
- This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Mutations in this gene cause familial cold autoinflammatory syndrome type 2. Alternative splicing results in multiple transcript variants.,NLRP12,CLR19.3,FCAS2,NALP12,PAN6,PYPAF7,RNO,RNO2,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Caspases,NLRP12
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分子量
- 31kDa/101kDa/107kDa/113kDa/114kDa/120kDa
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基因ID
- 91662
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UniProt
- P59046
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途径
- Positive Regulation of Endopeptidase Activity, Inflammasome
抗原
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