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NLRP1 抗体 (AA 1000-1100)

This anti-NLRP1 antibody is a 兔 多克隆 antibody detecting NLRP1 in WB, IHC 和 IF. Suitable for 人.
产品编号 ABIN7268935
发货至: 中国

Quick Overview for NLRP1 抗体 (AA 1000-1100) (ABIN7268935)

抗原

See all NLRP1 抗体
NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))

适用

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宿主

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克隆类型

  • 44
多克隆

标记

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This NLRP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    AA 1000-1100

    原理

    NLRP1 Rabbit pAb

    序列

    TGEMSNSTSS LKRQRLGSER AASHVAQANL KLLDVSKIFP IAEIAGKSHE ESSPEVVPVE LLCVPSPASQ GDLHTKPLGT DDDFWGPTGP VATEVVDKEK N

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthetic peptide corresponding to a sequence within amino acids 1000-1100 of human NLRP1 (NP_001028225.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))

    别名

    NLRP1

    背景

    This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined.,NLRP1,AIADK,CARD7,CIDED,CLR17.1,DEFCAP,DEFCAP-L/S,MSPC,NAC,NALP1,PP1044,SLEV1,VAMAS1,Cell Biology & Developmental Biology,Apoptosis,Caspases,NLRP1

    分子量

    46kDa/83kDa/154-165kDa

    基因ID

    22861

    UniProt

    Q9C000

    途径

    Positive Regulation of Endopeptidase Activity, Inflammasome
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