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Neuregulin 3 抗体

This anti-Neuregulin 3 antibody is a 兔 单克隆 antibody detecting Neuregulin 3 in WB. Suitable for 人.
产品编号 ABIN7268859
发货至: 中国

Quick Overview for Neuregulin 3 抗体 (ABIN7268859)

抗原

See all Neuregulin 3 (NRG3) 抗体
Neuregulin 3 (NRG3)

适用

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宿主

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克隆类型

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  • 3
单克隆

标记

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This Neuregulin 3 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 原理

    Neuregulin-3 (NRG3) Rabbit mAb

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Monoclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthesized peptide derived from human Neuregulin-3 (Neuregulin-3 (NRG3))

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Neuregulin 3 (NRG3)

    别名

    NRG3

    背景

    This gene is a member of the neuregulin gene family. This gene family encodes ligands for the transmembrane tyrosine kinase receptors ERBB3 and ERBB4 - members of the epidermal growth factor receptor family. Ligand binding activates intracellular signaling cascades and the induction of cellular responses including proliferation, migration, differentiation, and survival or apoptosis. This gene encodes neuregulin 3 (NRG3). NRG3 has been shown to activate the tyrosine phosphorylation of its cognate receptor, ERBB4, and is thought to influence neuroblast proliferation, migration and differentiation by signalling through ERBB4. NRG3 also promotes mammary differentiation during embryogenesis. Linkage studies have implicated this gene as a susceptibility locus for schizophrenia and schizoaffective disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but their biological validity has not been verified.[provided by RefSeq, Sep 2009],HRG3, pro-NRG3,Cancer,ErbB-HER Signaling Pathway,Neuroscience,Signal Transduction,NRG3

    分子量

    56kDa

    基因ID

    10718

    UniProt

    P56975

    途径

    RTK signaling
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