Neuregulin 3 抗体
Our Local Distributor
北京 101111
Quick Overview for Neuregulin 3 抗体 (ABIN7268859)
抗原
See all Neuregulin 3 (NRG3) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- Neuregulin-3 (NRG3) Rabbit mAb
-
交叉反应
- 人, 小鼠, 大鼠
-
产品特性
- Monoclonal Antibodies
-
纯化方法
- Affinity purification
-
免疫原
- A synthesized peptide derived from human Neuregulin-3 (Neuregulin-3 (NRG3))
-
亚型
- IgG
-
-
-
-
应用备注
- WB,1:500 - 1:2000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- Neuregulin 3 (NRG3)
-
别名
- NRG3
-
背景
- This gene is a member of the neuregulin gene family. This gene family encodes ligands for the transmembrane tyrosine kinase receptors ERBB3 and ERBB4 - members of the epidermal growth factor receptor family. Ligand binding activates intracellular signaling cascades and the induction of cellular responses including proliferation, migration, differentiation, and survival or apoptosis. This gene encodes neuregulin 3 (NRG3). NRG3 has been shown to activate the tyrosine phosphorylation of its cognate receptor, ERBB4, and is thought to influence neuroblast proliferation, migration and differentiation by signalling through ERBB4. NRG3 also promotes mammary differentiation during embryogenesis. Linkage studies have implicated this gene as a susceptibility locus for schizophrenia and schizoaffective disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but their biological validity has not been verified.[provided by RefSeq, Sep 2009],HRG3, pro-NRG3,Cancer,ErbB-HER Signaling Pathway,Neuroscience,Signal Transduction,NRG3
-
分子量
- 56kDa
-
基因ID
- 10718
-
UniProt
- P56975
-
途径
- RTK signaling
抗原
-