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MAP3K8 抗体 (AA 1-100)

This anti-MAP3K8 antibody is a 兔 多克隆 antibody detecting MAP3K8 in WB. Suitable for 人.
产品编号 ABIN7268661
发货至: 中国

Quick Overview for MAP3K8 抗体 (AA 1-100) (ABIN7268661)

抗原

See all MAP3K8 抗体
MAP3K8 (Mitogen-Activated Protein Kinase Kinase Kinase 8 (MAP3K8))

适用

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宿主

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克隆类型

  • 85
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多克隆

标记

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This MAP3K8 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 1-100

    原理

    MAP3K8 Rabbit pAb

    序列

    MEYMSTGSDN KEEIDLLIKH LNVSDVIDIM ENLYASEEPA VYEPSLMTMC QDSNQNDERS KSLLLSGQEV PWLSSVRYGT VEDLLAFANH ISNTAKHFYG

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MAP3K8 (NP_005195.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    MAP3K8 (Mitogen-Activated Protein Kinase Kinase Kinase 8 (MAP3K8))

    别名

    MAP3K8

    背景

    This gene is an oncogene that encodes a member of the serine/threonine protein kinase family. The encoded protein localizes to the cytoplasm and can activate both the MAP kinase and JNK kinase pathways. This protein was shown to activate IkappaB kinases, and thus induce the nuclear production of NF-kappaB. This protein was also found to promote the production of TNF-alpha and IL-2 during T lymphocyte activation. This gene may also utilize a downstream in-frame translation start codon, and thus produce an isoform containing a shorter N-terminus. The shorter isoform has been shown to display weaker transforming activity. Alternate splicing results in multiple transcript variants that encode the same protein.,MAP3K8,AURA2,COT,EST,ESTF,MEKK8,TPL2,Tpl-2,c-COT,Cancer,Signal Transduction,Kinase,Serine/threonine kinases,PI3K-Akt Signaling Pathway,MAPK-Erk Signaling Pathway,MAPK-JNK Signaling Pathway,Cell Biology & Developmental Biology,Cytoskeleton,Actins,Immunology & Inflammation,B Cell Receptor Signaling Pathway,NF-kB Signaling Pathway,MAP3K8

    分子量

    49kDa/52kDa

    基因ID

    1326

    UniProt

    P41279

    途径

    PI3K-Akt Signaling, TCR Signaling
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