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MCM4 抗体

This anti-MCM4 antibody is a 兔 单克隆 antibody detecting MCM4 in WB. Suitable for 人.
产品编号 ABIN7268545
发货至: 中国

Quick Overview for MCM4 抗体 (ABIN7268545)

抗原

See all MCM4 抗体
MCM4 (Minichromosome Maintenance Deficient 4 (MCM4))

适用

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宿主

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克隆类型

  • 89
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单克隆

标记

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This MCM4 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 原理

    MCM4 Rabbit mAb

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Monoclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthesized peptide derived from human MCM4

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    MCM4 (Minichromosome Maintenance Deficient 4 (MCM4))

    别名

    MCM4

    背景

    The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 6 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of this protein by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex. This gene is mapped to a region on the chromosome 8 head-to-head next to the PRKDC/DNA-PK, a DNA-activated protein kinase involved in the repair of DNA double-strand breaks. Alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008],CDC21, CDC54, NKCD, NKGCD, P1-CDC21, hCdc21,Epigenetics & Nuclear Signaling,MCM4

    分子量

    97kDa

    基因ID

    4173

    UniProt

    P33991

    途径

    DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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