KDM2A 抗体
Quick Overview for KDM2A 抗体 (ABIN7268326)
抗原
See all KDM2A 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- KDM2A Rabbit pAb
-
交叉反应
- 人, 小鼠
-
产品特性
- Polyclonal Antibodies
-
纯化方法
- Affinity purification
-
免疫原
- Recombinant protein of human KDM2A.
-
亚型
- IgG
-
-
-
-
应用备注
- WB,1:500 - 1:2000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))
-
别名
- KDM2A
-
背景
- This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least six highly degenerated leucine-rich repeats. This family member plays a role in epigenetic silencing. It nucleates at CpG islands and specifically demethylates both mono- and di-methylated lysine-36 of histone H3. Alternative splicing results in multiple transcript variants.,KDM2A, CXXC8, FBL11, FBL7, FBXL11, JHDM1A, LILINA, lysine demethylase 2A,Epigenetic writers and erasers of core Histones,Epigenetic writers and erasers of core Histones_Demethylation,Epigenetics & Nuclear Signaling,KDM2A
-
分子量
- 69kDa/81kDa/89kDa/96kDa/132kDa
-
基因ID
- 22992
-
UniProt
- Q9Y2K7
-
途径
- Warburg Effect
抗原
-