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LIN7C 抗体 (AA 1-70)

This anti-LIN7C antibody is a 兔 多克隆 antibody detecting LIN7C in WB. Suitable for 人.
产品编号 ABIN7268269
发货至: 中国

Quick Overview for LIN7C 抗体 (AA 1-70) (ABIN7268269)

抗原

See all LIN7C 抗体
LIN7C (Lin-7 Homolog C (LIN7C))

适用

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宿主

  • 31

克隆类型

  • 31
多克隆

标记

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This LIN7C antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 1-70

    原理

    LIN7C Rabbit pAb

    序列

    MAALGEPVRL ERDICRAIEL LEKLQRSGEV PPQKLQALQR VLQSEFCNAV REVYEHVYET VDISSSPEVR

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human LIN7C (NP_060832.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    LIN7C (Lin-7 Homolog C (LIN7C))

    别名

    LIN7C

    背景

    Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C, CASK and APBA1 associates with the motor protein KIF17 to transport vesicles containing N-methyl-D-aspartate (NMDA receptor subunit NR2B along microtubules (By similarity. This complex may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12 and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.,LIN7C,LIN-7-C,LIN-7C,MALS-3,MALS3,VELI3,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Tight Junctions,Cytoskeleton,Neuroscience,LIN7C

    分子量

    21kDa

    基因ID

    55327

    UniProt

    Q9NUP9

    途径

    Synaptic Membrane
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