LIN28B 抗体
Our Local Distributor
北京 101111
Quick Overview for LIN28B 抗体 (ABIN7268267)
抗原
See all LIN28B 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- LIN28B Rabbit mAb
-
交叉反应
- 人
-
产品特性
- Monoclonal Antibodies
-
纯化方法
- Affinity purification
-
免疫原
- A synthesized peptide derived from human LIN28B
-
亚型
- IgG
-
-
-
-
应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- LIN28B (Lin-28 Homolog B (LIN28B))
-
别名
- LIN28B
-
背景
- The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3' UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation. [provided by RefSeq, Jun 2012],CSDD2,Cancer,Epigenetics & Nuclear Signaling,Tumor biomarkers,LIN28B
-
分子量
- 32kDa
-
基因ID
- 389421
-
UniProt
- Q6ZN17
抗原
-