Laminin gamma 1 抗体 (AA 1300-1609)
Quick Overview for Laminin gamma 1 抗体 (AA 1300-1609) (ABIN7268186)
抗原
See all Laminin gamma 1 (LAMC1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1300-1609
-
原理
- LAMC1 Rabbit pAb
-
序列
- IDQKLKDYED LREDMRGKEL EVKNLLEKGK TEQQTADQLL ARADAAKALA EEAAKKGRDT LQEANDILNN LKDFDRRVND NKTAAEEALR KIPAINQTIT EANEKTREAQ QALGSAAADA TEAKNKAHEA ERIASAVQKN ATSTKAEAER TFAEVTDLDN EVNNMLKQLQ EAEKELKRKQ DDADQDMMMA GMASQAAQEA EINARKAKNS VTSLLSIIND LLEQLGQLDT VDLNKLNEIE GTLNKAKDEM KVSDLDRKVS DLENEAKKQE AAIMDYNRDI EEIMKDIRNL EDIRKTLPSG CFNTPSIEKP
-
交叉反应
- 人, 小鼠, 大鼠
-
产品特性
- Polyclonal Antibodies
-
纯化方法
- Affinity purification
-
免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1300-1609 of human LAMC1 (NP_002284.3).
-
亚型
- IgG
-
-
anti-Laminin, gamma 1 (LAMC1) (all Isoforms) antibody
LAMC1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Laminin, gamma 1 (LAMC1) (AA 1-38) antibodyLAMC1 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal M1 unconjugated
anti-Laminin, gamma 1 (LAMC1) (AA 521-772) antibodyLAMC1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Laminin, gamma 1 (LAMC1) (AA 1333-1607) antibodyLAMC1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Laminin, gamma 1 (LAMC1) (AA 1-38) antibodyLAMC1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E6-B4 unconjugated
anti-Laminin, gamma 1 (LAMC1) (N-Term) antibodyLAMC1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Laminin, gamma 1 (LAMC1) antibodyLAMC1 适用: 小鼠 宿主: 兔 Polyclonal unconjugated
anti-Laminin, gamma 1 (LAMC1) (AA 1566-1579) antibodyLAMC1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Laminin, gamma 1 (LAMC1) (C-Term) antibodyLAMC1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Laminin, gamma 1 (LAMC1) (AA 526-1106) antibodyLAMC1 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
-
-
应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- Laminin gamma 1 (LAMC1) (Laminin, gamma 1 (LAMC1))
-
别名
- LAMC1
-
背景
- Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins, composed of 3 non identical chains: laminin alpha, beta and gamma. Some of the chains have been shown to differ with respect to their tissue distribution, presumably reflecting diverse functions in vivo. This gene encodes the gamma chain isoform laminin, gamma 1. The gamma 1 chain, formerly thought to be a beta chain, contains structural domains similar to beta chains, however, lacks the short alpha region separating domains I and II. The structural organization of this gene also suggested that it had diverged considerably from the beta chain genes. Embryos of transgenic mice in which both alleles of the gamma 1 chain gene were inactivated by homologous recombination, lacked basement membranes, indicating that laminin, gamma 1 chain is necessary for laminin heterotrimer assembly. It has been inferred by analogy with the strikingly similar 3' UTR sequence in mouse laminin gamma 1 cDNA, that multiple polyadenylation sites are utilized in human to generate the 2 different sized mRNAs (5.5 and 7.5 kb) seen on Northern analysis.,LAMC1,LAMB2,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Neuroscience,Neurodegenerative Diseases,LAMC1
-
分子量
- 177kDa
-
基因ID
- 3915
-
UniProt
- P11047
抗原
-
