KIF7 抗体 (AA 1044-1343)
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北京 101111
Quick Overview for KIF7 抗体 (AA 1044-1343) (ABIN7268137)
抗原
See all KIF7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1044-1343
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原理
- KIF7 Rabbit pAb
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序列
- QLDEAIEALD AAIEYKNEAI TCRQRVLRAS ASLLSQCEMN LMAKLSYLSS SETRALLCKY FDKVVTLREE QHQQQIAFSE LEMQLEEQQR LVYWLEVALE RQRLEMDRQL TLQQKEHEQN MQLLLQQSRD HLGEGLADSR RQYEARIQAL EKELGRYMWI NQELKQKLGG VNAVGHSRGG EKRSLCSEGR QAPGNEDELH LAPELLWLSP LTEGAPRTRE ETRDLVHAPL PLTWKRSSLC GEEQGSPEEL RQREAAEPLV GRVLPVGEAG LPWNFGPLSK PRRELRRASP GMIDVRKNPL
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交叉反应
- 人
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1044-1343 of human KIF7 (NP_940927.2).
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亚型
- IgG
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应用备注
- WB,1:200 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- KIF7 (Kinesin Family Member 7 (KIF7))
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别名
- KIF7
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背景
- This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.,KIF7,ACLS,AGBK,HLS2,JBTS12,UNQ340,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Motor Proteins,Hedgehog Signaling Pathway,Stem Cells,KIF7
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分子量
- 150kDa
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基因ID
- 374654
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UniProt
- Q2M1P5
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途径
- Hedgehog Signaling
抗原
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