KIF20B 抗体 (AA 1200-1500)
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北京 101111
Quick Overview for KIF20B 抗体 (AA 1200-1500) (ABIN7268126)
抗原
See all KIF20B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1200-1500
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原理
- KIF20B Rabbit pAb
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序列
- KHLLQLKEEE EETNRQETEK LKEELSASSA RTQNLKADLQ RKEEDYADLK EKLTDAKKQI KQVQKEVSVM RDEDKLLRIK INELEKKKNQ CSQELDMKQR TIQQLKEQLN NQKVEEAIQQ YERACKDLNV KEKIIEDMRM TLEEQEQTQV EQDQVLEAKL EEVERLATEL EKWKEKCNDL ETKNNQRSNK EHENNTDVLG KLTNLQDELQ ESEQKYNADR KKWLEEKMML ITQAKEAENI RNKEMKKYAE DRERFFKQQN EMEILTAQLT EKDSDLQKWR EERDQLVAAL EIQLKALISS N
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1200-1500 of human KIF20B (NP_057279.2).
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亚型
- IgG
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应用备注
- WB,1:200 - 1:2000,IF,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- KIF20B (Kinesin Family Member 20B (KIF20B))
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别名
- KIF20B
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背景
- Plus-end-directed motor enzyme that is required for completion of cytokinesis. Required for proper midbody organization and abscission in polarized cortical stem cells. Plays a role in the regulation of neuronal polarization by mediating the transport of specific cargos. Participates in the mobilization of SHTN1 and in the accumulation of PIP3 in the growth cone of primary hippocampal neurons in a tubulin and actin-dependent manner. In the developing telencephalon, cooperates with SHTN1 to promote both the transition from the multipolar to the bipolar stage and the radial migration of cortical neurons from the ventricular zone toward the superficial layer of the neocortex. Involved in cerebral cortex growth (By similarity. Acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression.,KIF20B,CT90,KRMP1,MPHOSPH1,MPP-1,MPP1,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Cytoskeleton,Motor Proteins,KIF20B
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分子量
- 59kDa/199kDa/206kDa/210kDa/214kDa
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基因ID
- 9585
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UniProt
- Q96Q89
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途径
- M Phase
抗原
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