IBTK 抗体 (AA 900-1200)
Quick Overview for IBTK 抗体 (AA 900-1200) (ABIN7267871)
抗原
See all IBTK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 900-1200
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原理
- IBTK Rabbit pAb
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序列
- GLNMAALLEA RSLDVLSDGV LKDLSEFYRK MIPAMDRRVI TPYQDGPDIS YLEVEDGDIF LKEEINMEQN HSETMFKKAK TKAKKKPRKR SDSSGGYNLS DIIQSPSSTG LLKSGKTNSV ESLPELLTSD SEGSYAGVGS PRDLQSPDFT TGFHSDKIEA KVKPYVNGTS PVYSREDLKP WEKSPILKIS APQPIPSNRI DTTSSASWVA GSFSPVSPPV VDLRTIMEIE ESRQKCGATP KSHLGKTVSH GVKLSQKQRK MIALTTKENN SGMNSMETVL FTPSKAPKPV NAWASSLHSV S
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交叉反应
- 人
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 900-1200 of human IBTK (NP_056340.2).
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亚型
- IgG
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anti-Inhibitor of Bruton Agammaglobulinemia Tyrosine Kinase (IBTK) (AA 586-613) antibody
IBTK 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB24652 unconjugated
anti-Inhibitor of Bruton Agammaglobulinemia Tyrosine Kinase (IBTK) (AA 589-617), (Middle Region) antibodyIBTK 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Inhibitor of Bruton Agammaglobulinemia Tyrosine Kinase (IBTK) (AA 1-1353) antibodyIBTK 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Inhibitor of Bruton Agammaglobulinemia Tyrosine Kinase (IBTK) (C-Term) antibodyIBTK 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- IBTK (Inhibitor of Bruton Agammaglobulinemia Tyrosine Kinase (IBTK))
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别名
- IBTK
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背景
- Bruton tyrosine kinase (BTK) is a protein tyrosine kinase that is expressed in B cells, macrophages, and neutrophils. The protein encoded by this gene binds to BTK and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription. This gene has a pseudogene on chromosome 18. Alternative splicing results in multiple transcript variants encoding distinct isoforms.,IBTK,BTBD26,BTKI,Signal Transduction,Kinase,IBTK
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分子量
- 26kDa/133kDa/150kDa
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基因ID
- 25998
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UniProt
- Q9P2D0
抗原
-
