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HAP1 抗体 (AA 1-240)

This anti-HAP1 antibody is a 兔 多克隆 antibody detecting HAP1 in WB. Suitable for 人.
产品编号 ABIN7267795
发货至: 中国

Quick Overview for HAP1 抗体 (AA 1-240) (ABIN7267795)

抗原

See all HAP1 抗体
HAP1 (Huntingtin Associated Protein 1 (HAP1))

适用

  • 16
  • 8
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宿主

  • 18
  • 4
  • 2

克隆类型

  • 21
  • 3
多克隆

标记

  • 21
  • 1
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  • 1
This HAP1 antibody is un-conjugated

应用范围

  • 20
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  • 7
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  • 2
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-240

    原理

    HAP1 Rabbit pAb

    序列

    MRPKRLGRCC AGSRLGPGDP AALTCAPSPS ASPAPEPSAQ PQARGTGQRV GSRATSGSQF LSEARTGARP ASEAGAKAGA RRPSAFSAIQ GDVRSMPDNS DAPWTRFVFQ GPFGSRATGR GTGKAAGIWK TPAAYVGRRP GVSGPERAAF IRELEEALCP NLPPPVKKIT QEDVKVMLYL LEELLPPVWE SVTYGMVLQR ERDLNTAARI GQSLVKQNSV LMEENSKLEA LLGSAKEEIL

    交叉反应

    小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human HAP1 (NP_817084.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    HAP1 (Huntingtin Associated Protein 1 (HAP1))

    别名

    HAP1

    背景

    Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.,HAP1;HAP2;HIP5;HLP;hHLP1,Signal Transduction,Neuroscience,Neurodegenerative Diseases,HAP1

    分子量

    66kDa/67kDa/69kDa/75kDa

    基因ID

    9001

    UniProt

    P54257

    途径

    Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Positive Regulation of Response to DNA Damage Stimulus
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