GSK3 alpha 抗体
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北京 101111
Quick Overview for GSK3 alpha 抗体 (ABIN7267467)
抗原
See all GSK3 alpha (GSK3a) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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原理
- [KO Validated] GSK3α Rabbit mAb
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Monoclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthesized peptide derived from human GSK3alpha
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IP,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- GSK3 alpha (GSK3a) (Glycogen Synthase Kinase 3 alpha (GSK3a))
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别名
- GSK3A
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背景
- This gene encodes a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase, and transcription factors, such as JUN. It also plays a role in the WNT and PI3K signaling pathways, as well as regulates the production of beta-amyloid peptides associated with Alzheimer's disease. [provided by RefSeq, Oct 2011],GSK3 alpha;GSK3A,Apoptosis,Apoptosis_Inhibition of Apoptosis,B Cell Receptor Signaling Pathway,Cardiovascular,Cell Adhesion,Cell Biology & Developmental Biology,Cell Cycle,Endocrine & Metabolism,Endocrine and metabolic diseases,Endocrine and metabolic diseases_Diabetes,Epigenetics & Nuclear Signaling,ErbB-HER Signaling Pathway,ESC Pluripotency and Differentiation,Heart,Heart_Hypertrophy,Immunology & Inflammation,Insulin Receptor Signaling Pathway,Kinase,Kinase_Serine/threonine kinases,MAPK-Erk Signaling Pathway,mTOR Signaling Pathway,Neurodegenerative Diseases,Neurodegenerative Diseases_Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimers Disease,Neuroscience,PI3K-Akt Signaling Pathway,PI3K-Akt Signaling Pathway_Akt downstream targets,Protein folding,Protein phosphorylation,Signal Transduction,Stem Cells,Translation Control,Translational Control_Regulation of eIF4 and p70 S6 Kinase,Wnt/β-Catenin Signaling Pathway,GSK3A
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分子量
- 51kDa
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基因ID
- 2931
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UniProt
- P49840
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途径
- PI3K-Akt Signaling, WNT signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, cAMP Metabolic Process, Cellular Glucan Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, BCR Signaling, Warburg Effect
抗原
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