Fibrillarin 抗体
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北京 101111
Quick Overview for Fibrillarin 抗体 (ABIN7267175)
抗原
See all Fibrillarin (FBL) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Fibrillarin/U3 RNP Rabbit mAb
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Monoclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthesized peptide derived from human Fibrillarin/U3 RNP
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Fibrillarin (FBL)
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别名
- FBL
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背景
- This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8 % of humans with the autoimmune disease scleroderma recognize fibrillarin. [provided by RefSeq, Jul 2008],FIB, FLRN, RNU3IP1,Epigenetics & Nuclear Signaling,RNA Binding,FBL
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分子量
- 33kDa
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基因ID
- 2091
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UniProt
- P22087
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途径
- Ribonucleoside Biosynthetic Process
抗原
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