Endoglin 抗体 (AA 26-306)
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北京 101111
Quick Overview for Endoglin 抗体 (AA 26-306) (ABIN7266939)
抗原
See all Endoglin (ENG) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 26-306
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原理
- CD105/Endoglin Rabbit pAb
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序列
- ETVHCDLQPV GPERGEVTYT TSQVSKGCVA QAPNAILEVH VLFLEFPTGP SQLELTLQAS KQNGTWPREV LLVLSVNSSV FLHLQALGIP LHLAYNSSLV TFQEPPGVNT TELPSFPKTQ ILEWAAERGP ITSAAELNDP QSILLRLGQA QGSLSFCMLE ASQDMGRTLE WRPRTPALVR GCHLEGVAGH KEAHILRVLP GHSAGPRTVT VKVELSCAPG DLDAVLILQG PPYVSWLIDA NHNMQIWTTG EYSFKIFPEK NIRGFKLPDT PQGLLGEARM L
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交叉反应
- 人, 小鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 26-306 of human CD105/Endoglin (NP_001108225.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Endoglin (ENG)
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别名
- ENG
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背景
- This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,END,HHT1,ORW1,CD105,ENG,endoglin,Cancer,Tumor biomarkers,Immunology & Inflammation,CD markers,Stem Cells,Endothelial Progenitors,Mesenchymal Stem Cells,Cardiovascular,Cardiovascular Markers,Endothelial Cells,ENG
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分子量
- 67kDa/70kDa
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基因ID
- 2022
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UniProt
- P17813
抗原
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