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Dynamitin 抗体 (AA 280-401)

This anti-Dynamitin antibody is a 兔 多克隆 antibody detecting Dynamitin in WB. Suitable for 人.
产品编号 ABIN7266851
发货至: 中国

Quick Overview for Dynamitin 抗体 (AA 280-401) (ABIN7266851)

抗原

See all Dynamitin (DCTN2) 抗体
Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))

适用

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宿主

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克隆类型

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多克隆

标记

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This Dynamitin antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 280-401

    原理

    DCTN2 Rabbit pAb

    序列

    VLDQVEARLQ SVLGKVNEIA KHKASVEDAD TQSKVHQLYE TIQRWSPIAS TLPELVQRLV TIKQLHEQAM QFGQLLTHLD TTQQMIANSL KDNTTLLTQV QTTMRENLAT VEGNFASIDE RM

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 280-401 of human DCTN2 (NP_006391.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))

    别名

    DCTN2

    背景

    This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.,DCTN2,DCTN50,DYNAMITIN,HEL-S-77,RBP50,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Cytoskeleton,Motor Proteins,Neuroscience,Neurodegenerative Diseases,DCTN2

    分子量

    44kDa

    基因ID

    10540

    UniProt

    Q13561

    途径

    M Phase, Ribonucleoprotein Complex Subunit Organization
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