DUSP8 抗体
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北京 101111
Quick Overview for DUSP8 抗体 (ABIN7266849)
抗原
See all DUSP8 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- DUSP8 Rabbit pAb
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein of human DUSP8
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亚型
- IgG
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应用备注
- WB,1:200 - 1:1000,IF,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- DUSP8 (Dual Specificity Phosphatase 8 (DUSP8))
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别名
- DUSP8
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背景
- The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates SAPK/JNK and p38, is expressed predominantly in the adult brain, heart, and skeletal muscle, is localized in the cytoplasm, and is induced by nerve growth factor and insulin. An intronless pseudogene for DUSP8 is present on chromosome 10q11.2.,DUSP8,C11orf81,HB5,HVH-5,HVH8,Signal Transduction,DUSP8
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分子量
- 65kDa
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基因ID
- 1850
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UniProt
- Q13202
抗原
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