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DUSP8 抗体 (C-Term)

DUSP8 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB5874 unconjugated
产品编号 ABIN392868
发货至: 中国
  • 抗原 See all DUSP8 抗体
    DUSP8 (Dual Specificity Phosphatase 8 (DUSP8))
    抗原表位
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    AA 456-487, C-Term
    适用
    • 22
    • 11
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 21
    • 1
    克隆类型
    • 22
    多克隆
    标记
    • 10
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DUSP8 antibody is un-conjugated
    应用范围
    • 15
    • 10
    • 8
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This DUSP8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 456-487 amino acids from the C-terminal region of human DUSP8.
    克隆位点
    RB5874
    亚型
    Ig Fraction
    Top Product
    Discover our top product DUSP8 Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    DUSP8 (Dual Specificity Phosphatase 8 (DUSP8))
    别名
    DUSP8 (DUSP8 产品)
    别名
    zgc:77593 antibody, C11orf81 antibody, HB5 antibody, HVH-5 antibody, HVH8 antibody, 5530400B01Rik antibody, AI593498 antibody, Nttp1 antibody, Hb5 antibody, M3/6 antibody, DUSP8 antibody, dual specificity phosphatase 8 antibody, dual specificity phosphatase 8a antibody, dual specificity protein phosphatase 8 antibody, DUSP8 antibody, dusp8 antibody, dusp8a antibody, DSP8 antibody, Dusp8 antibody, LOC615727 antibody
    背景
    DUSP8 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. DUSP8 inactivates SAPK/JNK and p38, is expressed predominantly in the adult brain, heart, and skeletal muscle, is localized in the cytoplasm, and is induced by nerve growth factor and insulin.
    分子量
    65827
    基因ID
    1850
    NCBI登录号
    NP_004411
    UniProt
    Q13202
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