DNMT1 抗体
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北京 101111
Quick Overview for DNMT1 抗体 (ABIN7266808)
抗原
See all DNMT1 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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原理
- [KO Validated] DNMT1 Rabbit mAb
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Monoclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthesized peptide derived from human DNMT1.
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200,ChIP,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- DNMT1 (DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))
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别名
- DNMT1
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背景
- This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016],ADCADN,AIM,CXXC9,DNMT,HSN1E,MCMT,m.HsaI,DNMT1,Epigenetic writers and erasers of core Histones,Epigenetic writers and erasers of core Histones_DNA methylation,Epigenetics & Nuclear Signaling,Protein phosphorylation,DNMT1
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分子量
- 183kDa
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基因ID
- 1786
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UniProt
- P26358
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途径
- SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
抗原
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