DVL1 抗体 (AA 510-640)
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北京 101111
Quick Overview for DVL1 抗体 (AA 510-640) (ABIN7266796)
抗原
See all DVL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 510-640
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原理
- DVL1 Rabbit pAb
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序列
- GQGYPYQYPG PPPCFPPAYQ DPGFSYGSGS TGSQQSEGSK SSGSTRSSRR APGREKERRA AGAGGSGSES DHTAPSGVGS SWRERPAGQL SRGSSPRSQA SATAPGLPPP HPTTKAYTVV GGPPGGPPVR E
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 510-640 of human DVL1 (NP_004412.2).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- DVL1 (Dishevelled Segment Polarity Protein 1 (DVL1))
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别名
- DVL1
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背景
- DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.,DVL1,DRS2,DVL,DVL1L1,DVL1P1,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Signal Transduction,mTOR Signaling Pathway,Cell Biology & Developmental Biology,Hippo Signaling Pathway,Wnt/β-Catenin Signaling Pathway,Stem Cells,DVL1
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分子量
- 72kDa/75kDa
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基因ID
- 1855
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UniProt
- O14640
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途径
- WNT signaling, Synaptic Membrane, Skeletal Muscle Fiber Development
抗原
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