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DNASE1 抗体 (AA 30-235)

This anti-DNASE1 antibody is a 兔 多克隆 antibody detecting DNASE1 in WB 和 IF. Suitable for 人.
产品编号 ABIN7266733
发货至: 中国

Quick Overview for DNASE1 抗体 (AA 30-235) (ABIN7266733)

抗原

See all DNASE1 抗体
DNASE1 (Deoxyribonuclease I (DNASE1))

适用

  • 69
  • 26
  • 17
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宿主

  • 68
  • 17
  • 1

克隆类型

  • 71
  • 15
多克隆

标记

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This DNASE1 antibody is un-conjugated

应用范围

  • 73
  • 30
  • 25
  • 15
  • 14
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  • 13
  • 11
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  • 3
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  • 2
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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

    • 15
    • 11
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 30-235

    原理

    DNASE1 Rabbit pAb

    序列

    IQTFGETKMS NATLVSYIVQ ILSRYDIALV QEVRDSHLTA VGKLLDNLNQ DAPDTYHYVV SEPLGRNSYK ERYLFVYRPD QVSAVDSYYY DDGCEPCGND TFNREPAIVR FFSRFTEVRE FAIVPLHAAP GDAVAEIDAL YDVYLDVQEK WGLEDVMLMG DFNAGCSYVR PSQWSSIRLW TSPTFQWLIP DSADTTATPT HCAYDR

    交叉反应

    小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 30-235 of human DNASE1 (NP_005214.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    DNASE1 (Deoxyribonuclease I (DNASE1))

    别名

    DNASE1

    背景

    This gene encodes a member of the DNase family. This protein is stored in the zymogen granules of the nuclear envelope and functions by cleaving DNA in an endonucleolytic manner. At least six autosomal codominant alleles have been characterized, DNASE1*1 through DNASE1*6, and the sequence of DNASE1*2 represented in this record. Mutations in this gene have been associated with systemic lupus erythematosus (SLE), an autoimmune disease. A recombinant form of this protein is used to treat the one of the symptoms of cystic fibrosis by hydrolyzing the extracellular DNA in sputum and reducing its viscosity. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.,DNASE1,DNL1,DRNI,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Endocrine & Metabolism,DNASE1

    分子量

    19kDa/31kDa

    基因ID

    1773

    UniProt

    P24855
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