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DAXX 抗体 (AA 501-740)

This anti-DAXX antibody is a 兔 多克隆 antibody detecting DAXX in WB. Suitable for 人.
产品编号 ABIN7266714
发货至: 中国

Quick Overview for DAXX 抗体 (AA 501-740) (ABIN7266714)

抗原

See all DAXX 抗体
DAXX (Death-Domain Associated Protein (DAXX))

适用

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宿主

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克隆类型

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多克隆

标记

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This DAXX antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 501-740

    原理

    Daxx Rabbit pAb

    序列

    QISNEKNLEP GKQISRSSGE QQNKGRIVSP SLLSEEPLAP SSIDAESNGE QPEELTLEEE SPVSQLFELE IEALPLDTPS SVETDISSSR KQSEEPFTTV LENGAGMVSS TSFNGGVSPH NWGDSGPPCK KSRKEKKQTG SGPLGNSYVE RQRSVHEKNG KKICTLPSPP SPLASLAPVA DSSTRVDSPS HGLVTSSLCI PSPARLSQTP HSQPPRPGTC KTSVATQCDP EEIIVLSDSD

    交叉反应

    人, 小鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 501-740 of human Daxx (NP_001135441.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    DAXX (Death-Domain Associated Protein (DAXX))

    别名

    DAXX

    背景

    This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants.,DAXX,BING2,DAP6,EAP1,Epigenetics & Nuclear Signaling,Chromatin Remodeling,Signal Transduction,MAPK-JNK Signaling Pathway,MAPK-P38 Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Death Receptor Signaling Pathway,Neuroscience,Neurodegenerative Diseases,DAXX

    分子量

    73kDa/75kDa/76kDa/78kDa/81kDa

    基因ID

    1616

    UniProt

    Q9UER7

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway
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