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DDB2 抗体

This anti-DDB2 antibody is a 兔 单克隆 antibody detecting DDB2 in WB. Suitable for 人.
产品编号 ABIN7266674
发货至: 中国

Quick Overview for DDB2 抗体 (ABIN7266674)

抗原

See all DDB2 抗体
DDB2 (Damage-Specific DNA Binding Protein 2, 48kDa (DDB2))

适用

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宿主

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克隆类型

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单克隆

标记

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This DDB2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 原理

    DDB2 Rabbit mAb

    交叉反应

    人, 小鼠

    产品特性

    Monoclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthesized peptide derived from human DDB2

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    DDB2 (Damage-Specific DNA Binding Protein 2, 48kDa (DDB2))

    别名

    DDB2

    背景

    This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014],DDBB, UV-DDB2, XPE,Cell Biology & Developmental Biology,DNA Damage & Repair,Epigenetics & Nuclear Signaling,Ubiquitin,Ubiquitin_Ubiquitin-Proteasome Signaling Pathway,DDB2

    分子量

    45kDa

    基因ID

    1643

    UniProt

    Q92466

    途径

    DNA Damage Repair
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