CISH 抗体 (AA 17-130)
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Quick Overview for CISH 抗体 (AA 17-130) (ABIN7266663)
抗原
See all CISH 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 17-130
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原理
- CISH Rabbit pAb
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序列
- TGQRPLWAPS LELPKPVMQP LPAGAFLEEV AEGTPAQTES EPKVLDPEED LLCIAKTFSY LRESGWYWGS ITASEARQHL QKMPEGTFLV RDSTHPSYLF TLSVKTTRGP TNVR
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 17-130 of human CISH (NP_659508.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- CISH (Cytokine Inducible SH2-Containing Protein (CISH))
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别名
- CISH
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背景
- The protein encoded by this gene contains a SH2 domain and a SOCS box domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by IL2, IL3, GM-CSF and EPO in hematopoietic cells. Proteasome-mediated degradation of this protein has been shown to be involved in the inactivation of the erythropoietin receptor. Multiple transcript variants encoding different isoforms have been found for this gene.,CISH,BACTS2,CIS,CIS-1,G18,SOCS,Epigenetics & Nuclear Signaling,Signal Transduction,Immunology & Inflammation,IL-6 Receptor Signaling Pathway,CISH
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分子量
- 28kDa/29kDa/30kDa
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基因ID
- 1154
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UniProt
- Q9NSE2
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途径
- JAK/STAT Signaling, Response to Growth Hormone Stimulus
抗原
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