CDK8 抗体
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北京 101111
Quick Overview for CDK8 抗体 (ABIN7266596)
抗原
See all CDK8 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- CDK8 Rabbit mAb
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Monoclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthesized peptide derived from human CDK8
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- CDK8 (Cyclin-Dependent Kinase 8 (CDK8))
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别名
- CDK8
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背景
- This gene encodes a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit, cyclin C, are components of the Mediator transcriptional regulatory complex, involved in both transcriptional activation and repression by phosphorylation of the carboxy-terminal domain of the largest subunit of RNA polymerase II. This kinase regulates transcription by targeting the cyclin-dependent kinase 7 subunits of the general transcription initiation factor IIH, thus providing a link between the Mediator complex and the basal transcription machinery. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016],K35,Cell Biology & Developmental Biology,Cell Cycle,Epigenetics & Nuclear Signaling,Kinase,Kinase_Serine/threonine kinases,Notch Signaling Pathway,Signal Transduction,Wnt/β-Catenin Signaling Pathway,CDK8
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分子量
- 53kDa
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基因ID
- 1024
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UniProt
- P49336
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途径
- Cell Division Cycle, Regulation of Lipid Metabolism by PPARalpha
抗原
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