Coronavirus Spike Glycoprotein 抗体
CoV S
适用: SARS Coronavirus-2 (SARS-CoV-2)
ELISA, WB, IF, IP
宿主: 兔
Polyclonal
unconjugated
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- 抗原 See all Coronavirus Spike Glycoprotein (CoV S) 抗体
- Coronavirus Spike Glycoprotein (CoV S)
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适用
- SARS Coronavirus-2 (SARS-CoV-2)
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Coronavirus Spike Glycoprotein antibody is un-conjugated
- 应用范围
- ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
- 原理
- SARS-CoV-2 Spike Rabbit pAb
- 交叉反应
- SARS Coronavirus-2 (SARS-CoV-2)
- 产品特性
- Polyclonal Antibodies
- 纯化方法
- Affinity purification
- 免疫原
- A synthetic peptide of SARS-CoV-2 Spike.
- 亚型
- IgG
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- 应用备注
- ELISA,1:40000-1:160000,WB,1:500 - 1:2000,IF,1:50 - 1:200,IP,1:50 - 1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- Coronavirus Spike Glycoprotein (CoV S)
- 别名
- Spike (CoV S 产品)
- 别名
- E2 antibody, E2 glycoprotein precursor antibody, S antibody
- 物质类
- Viral Protein
- 背景
- The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. The spike is essential for both host specificity and viral infectivity. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. It''s been reported that SARS-CoV-2 (COVID-19 coronavirus, 2019-nCoV) can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. The main functions for the Spike protein are summarized as: Mediate receptor binding and membrane fusion, Defines the range of the hosts and specificity of the virus, Main component to bind with the neutralizing antibody, Key target for vaccine design, Can be transmitted between different hosts through gene recombination or mutation of the receptor binding domain (RBD), leading to a higher mortality rate.,Spike
- 基因ID
- 43740568
- UniProt
- P0DTC2
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