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C4A 抗体

This anti-C4A antibody is a 兔 单克隆 antibody detecting C4A in WB 和 IF. Suitable for 人.
产品编号 ABIN7266481
发货至: 中国

Quick Overview for C4A 抗体 (ABIN7266481)

抗原

See all C4A (C4a) 抗体
C4A (C4a) (Complement Fragment C4a (C4a))

适用

  • 22
  • 8
  • 5
  • 2

宿主

  • 24
  • 8

克隆类型

  • 22
  • 10
单克隆

标记

  • 25
  • 3
  • 2
  • 1
  • 1
This C4A antibody is un-conjugated

应用范围

  • 24
  • 20
  • 13
  • 11
  • 6
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF)
  • 原理

    Complement C4A Rabbit mAb

    交叉反应

    产品特性

    Monoclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthesized peptide derived from human Complement C4A

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    C4A (C4a) (Complement Fragment C4a (C4a))

    别名

    C4A

    背景

    This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain is cleaved to release C4 anaphylatoxin, an antimicrobial peptide and a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014],C4, C4A2, C4A3, C4A4, C4A6, C4AD, C4S, CO4, CPAMD2, RG,Cell Intrinsic Innate Immunity Signaling Pathway,Immunology & Inflammation,C4A

    分子量

    193kDa

    基因ID

    720

    UniProt

    P0C0L4

    途径

    Complement System
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