CD276 抗体 (AA 100-200)
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北京 101111
Quick Overview for CD276 抗体 (AA 100-200) (ABIN7266182)
抗原
See all CD276 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 100-200
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原理
- B7-H3/CD276 Rabbit pAb
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序列
- LAQGNASLRL QRVRVADEGS FTCFVSIRDF GSAAVSLQVA APYSKPSMTL EPNKDLRPGD TVTITCSSYQ GYPEAEVFWQ DGQGVPLTGN VTTSQMANEQ G
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交叉反应
- 人, 小鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthetic peptide corresponding to a sequence within amino acids 100-200 of human B7-H3/CD276 (NP_001019907.1).
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亚型
- IgG
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应用备注
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WB,1:500 - 1:2000
IHC-P, 1:50 - 1:200 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- CD276
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别名
- CD276
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背景
- The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,CD276;4Ig-B7-H3;B7-H3;B7H3;B7RP-2,Cancer,Tumor biomarkers,Immunology & Inflammation,CD markers,Stem Cells,Hematopoietic Progenitors,CD276
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分子量
- 33kDa/52kDa/57kDa
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基因ID
- 80381
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UniProt
- Q5ZPR3
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途径
- Cancer Immune Checkpoints
抗原
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