FLASH 抗体 (AA 1733-1982)
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Quick Overview for FLASH 抗体 (AA 1733-1982) (ABIN7266108)
抗原
See all FLASH (CASP8AP2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1733-1982
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原理
- CASP8AP2 Rabbit pAb
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序列
- TVGAFIDLTQ DASSEAKSEG NHPALAVEDL GCGVIQVDED NCKEEKAQVA NRPLKCIVEE TYIDLTTESP SSCEVKKDEL KSEPGSNCDN SELPGTLHNS HKKRRNISDL NHPHKKQRKE TDLTNKEKTK KPTQDSCENT EAHQKKASKK KAPPVTKDPS SLKATPGIKD SSAALATSTS LSAKNVIKKK GEIIILWTRN DDREILLECQ KRGPSFKTFA YLAAKLDKNP NQVSERFQQL MKLFEKSKCR
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交叉反应
- 人
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1733-1982 of human CASP8AP2 (NP_036247.1).
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- FLASH (CASP8AP2) (CASP8 Associated Protein 2 (CASP8AP2))
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别名
- CASP8AP2
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背景
- This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.,CASP8AP2,CED-4,FLASH,RIP25,Cell Biology & Developmental Biology,Apoptosis,CASP8AP2
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分子量
- 222kDa
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基因ID
- 9994
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UniProt
- Q9UKL3
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途径
- Chromatin Binding, Positive Regulation of Endopeptidase Activity
抗原
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