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FLASH 抗体 (N-Term)

This 兔 多克隆 antibody specifically detects FLASH in WB. It exhibits reactivity toward 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, Pig 和 兔.It has been mentioned in 1 publication
产品编号 ABIN2784233
发货至: 中国
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Quick Overview for FLASH 抗体 (N-Term) (ABIN2784233)

抗原

See all FLASH (CASP8AP2) 抗体
FLASH (CASP8AP2) (CASP8 Associated Protein 2 (CASP8AP2))

适用

人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, Pig, 兔

宿主

  • 24
兔

克隆类型

  • 24
多克隆

标记

  • 17
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This FLASH antibody is un-conjugated

应用范围

  • 17
  • 5
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    N-Term

    原理

    CASP8AP2 Antibody - N-terminal region

    序列

    SLKKNISALI KTARVEINRK DEEISNLHQR LSEFPHFRNN HKTARTFDTV

    预测反应

    Cow: 93%, Dog: 86%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 93%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against CASP8AP2. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human CASP8AP2
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8096319

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • Lee, Pi, Lee: "Buffer optimization for high resolution of human lung cancer tissue proteins by two-dimensional gel electrophoresis." in: Biotechnology letters, Vol. 31, Issue 1, pp. 31-7, (2008) (PubMed).

  • 抗原

    FLASH (CASP8AP2) (CASP8 Associated Protein 2 (CASP8AP2))

    别名

    CASP8AP2

    背景

    Background Information: This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.

    Gene Name: caspase 8 associated protein 2

    Alternative Symbols: CED-4, FLASH, RIP25

    Protein Name: CASP8-associated protein 2

    分子量

    223kDa

    基因ID

    9994

    NCBI登录号

    NP_036247

    UniProt

    Q9UKL3

    途径

    Chromatin Binding, Positive Regulation of Endopeptidase Activity
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