FLASH 抗体 (N-Term)
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北京 101111
Quick Overview for FLASH 抗体 (N-Term) (ABIN2784233)
抗原
See all FLASH (CASP8AP2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- CASP8AP2 Antibody - N-terminal region
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序列
- SLKKNISALI KTARVEINRK DEEISNLHQR LSEFPHFRNN HKTARTFDTV
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预测反应
- Cow: 93%, Dog: 86%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 93%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against CASP8AP2. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human CASP8AP2
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8096319
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "Buffer optimization for high resolution of human lung cancer tissue proteins by two-dimensional gel electrophoresis." in: Biotechnology letters, Vol. 31, Issue 1, pp. 31-7, (2008) (PubMed).
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- FLASH (CASP8AP2) (CASP8 Associated Protein 2 (CASP8AP2))
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别名
- CASP8AP2
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背景
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Background Information: This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.
Gene Name: caspase 8 associated protein 2
Alternative Symbols: CED-4, FLASH, RIP25
Protein Name: CASP8-associated protein 2
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分子量
- 223kDa
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基因ID
- 9994
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NCBI登录号
- NP_036247
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UniProt
- Q9UKL3
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途径
- Chromatin Binding, Positive Regulation of Endopeptidase Activity
抗原
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