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BAG4 抗体 (AA 1-100)

This anti-BAG4 antibody is a 兔 多克隆 antibody detecting BAG4 in WB 和 IHC. Suitable for 人.
产品编号 ABIN7265852
发货至: 中国

Quick Overview for BAG4 抗体 (AA 1-100) (ABIN7265852)

抗原

See all BAG4 抗体
BAG4 (BCL2-Associated Athanogene 4 (BAG4))

适用

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  • 1

宿主

  • 45
  • 4
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  • 1

克隆类型

  • 52
  • 1
多克隆

标记

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This BAG4 antibody is un-conjugated

应用范围

  • 35
  • 20
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  • 3
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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 9
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    • 1
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    AA 1-100

    原理

    BAG4 Rabbit pAb

    序列

    MSALRRSGYG PSDGPSYGRY YGPGGGDVPV HPPPPLYPLR PEPPQPPISW RVRGGGPAET TWLGEGGGGD GYYPSGGAWP EPGRAGGSHQ SLNSYTNGAY

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    A synthetic peptide corresponding to a sequence within amino acids 1-100 of human BAG4 (NP_001191807.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:100 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    BAG4 (BCL2-Associated Athanogene 4 (BAG4))

    别名

    BAG4

    背景

    The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. This protein was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3), and thereby negatively regulates downstream cell death signaling. The regulatory role of this protein in cell death was demonstrated in epithelial cells which undergo apoptosis while integrin mediated matrix contacts are lost. Alternatively spliced transcript variants encoding distinct isoforms have been identified.,BAG4,BAG-4,SODD,Cell Biology & Developmental Biology,Apoptosis,BAG4

    分子量

    45kDa/49kDa

    基因ID

    9530

    UniProt

    O95429

    途径

    Regulation of Actin Filament Polymerization
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