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ARNT 抗体 (AA 1-260)

This anti-ARNT antibody is a 兔 多克隆 antibody detecting ARNT in IF. Suitable for 人.
产品编号 ABIN7265683
发货至: 中国

Quick Overview for ARNT 抗体 (AA 1-260) (ABIN7265683)

抗原

See all ARNT 抗体
ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))

适用

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宿主

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克隆类型

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多克隆

标记

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This ARNT antibody is un-conjugated

应用范围

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Immunofluorescence (IF)
  • 抗原表位

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    AA 1-260

    原理

    HIF1β/ARNT Rabbit pAb

    序列

    MAATTANPEM TSDVPSLGPA IASGNSGPGI QGGGAIVQRA IKRRPGLDFD DDGEGNSKFL RCDDDQMSND KERFARSDDE QSSADKERLA RENHSEIERR RRNKMTAYIT ELSDMVPTCS ALARKPDKLT ILRMAVSHMK SLRGTGNTST DGSYKPSFLT DQELKHLILE AADGFLFIVS CETGRVVYVS DSVTPVLNQP QSEWFGSTLY DQVHPDDVDK LREQLSTSEN ALTGRILDLK TGTVKKEGQQ SSMRMCMGSR

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human HIF1beta/ARNT (NP_001659.1).

    亚型

    IgG
  • 应用备注

    IF,1:50 - 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))

    别名

    ARNT

    背景

    This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013],ARNT,HIF-1-beta,HIF-1beta,HIF1-beta,HIF1B,HIF1BETA,TANGO,bHLHe2,Epigenetics & Nuclear Signaling,Transcription Factors,Nuclear Receptor Signaling,Cancer,Invasion and Metastasis,Signal Transduction,mTOR Signaling Pathway,Endocrine & Metabolism,Nucleotide metabolism,Cardiovascular,Angiogenesis,Hypoxia,HIF,ARNT

    分子量

    84kDa/85kDa/86kDa

    基因ID

    405

    UniProt

    P27540

    途径

    Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Warburg Effect
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