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ALDH2 抗体

ALDH2 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7265538
发货至: 中国
  • 抗原 See all ALDH2 抗体
    ALDH2 (Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2))
    适用
    • 65
    • 24
    • 24
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 54
    • 12
    • 2
    克隆类型
    • 51
    • 17
    单克隆
    标记
    • 41
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This ALDH2 antibody is un-conjugated
    应用范围
    • 54
    • 31
    • 28
    • 14
    • 10
    • 10
    • 9
    • 9
    • 1
    Western Blotting (WB)
    原理
    ALDH2 Rabbit mAb
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthesized peptide derived from human ALDH2
    亚型
    IgG
    Top Product
    Discover our top product ALDH2 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    ALDH2 (Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2))
    别名
    ALDH2 (ALDH2 产品)
    背景
    This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50 % of East Asians have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among East Asians than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Nov 2016],ALDH-E2, ALDHI, ALDM,Cancer,Cardiovascular,Endocrine & Metabolism,Heart,Heart_Cardiac metabolism,Mitochondrial metabolism,Mitochondrial metabolism_Mitochondrial markers,Signal Transduction,ALDH2
    分子量
    56kDa
    基因ID
    217
    UniProt
    P05091
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