OGG1 抗体
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北京 101111
Quick Overview for OGG1 抗体 (ABIN7265349)
抗原
See all OGG1 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- OGG1 Rabbit mAb
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Monoclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- A synthesized peptide derived from human OGG1
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亚型
- IgG
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))
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别名
- OGG1
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背景
- This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined. [provided by RefSeq, Aug 2008],HMMH, HOGG1, MUTM, OGH1,Cancer,DNA Damage & Repair,Epigenetics & Nuclear Signaling,Tumor biomarkers,OGG1
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分子量
- 39kDa
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基因ID
- 4968
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UniProt
- O15527
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途径
- DNA Damage Repair
抗原
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