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ABAT 抗体

ABAT 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
产品编号 ABIN7265336
发货至: 中国
  • 抗原 See all ABAT 抗体
    ABAT (4-Aminobutyrate Aminotransferase (ABAT))
    适用
    • 45
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    宿主
    • 41
    • 5
    克隆类型
    • 41
    • 5
    单克隆
    标记
    • 26
    • 1
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    This ABAT antibody is un-conjugated
    应用范围
    • 39
    • 14
    • 13
    • 13
    • 10
    • 9
    • 4
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    • 4
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    原理
    GABA transaminase (ABAT) Rabbit mAb
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Monoclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    A synthesized peptide derived from human GABA transaminase (GABA transaminase (ABAT))
    亚型
    IgG
    Top Product
    Discover our top product ABAT Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    ABAT (4-Aminobutyrate Aminotransferase (ABAT))
    别名
    ABAT (ABAT 产品)
    背景
    4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95 % similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. [provided by RefSeq, Jul 2008],GABA-AT, GABAT, NPD009,Amino acid metabolism,Cancer,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial metabolism_Mitochondrial markers,Neurodegenerative Diseases Markers,Neuroscience,Other Neurological disorders,Signal Transduction,ABAT
    分子量
    50kDa
    基因ID
    18
    UniProt
    P80404
    途径
    Monocarboxylic Acid Catabolic Process
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