GPR84 抗体 (Extracellular) (PE)
Quick Overview for GPR84 抗体 (Extracellular) (PE) (ABIN7237670)
抗原
See all GPR84 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 166-180, Extracellular
-
原理
- A Rabbit Polyclonal Antibody to GPR84 (extracellular) conjugated to the fluorescent dye Phycoerythrin (PE)
-
特异性
- 2nd extracellular loop
-
交叉反应
- 人, 小鼠, 大鼠
-
预测反应
- Human - 14,15 amino acid residues identical, mouse,rat - 13
-
产品特性
- Extracellular, 2nd loop
-
纯化方法
- Affinity purified on immobilized antigen.
-
免疫原
-
Immunogen: Synthetic peptide
Immunogen Sequence: Peptide CT(S)SFDRIRGRPYTT, corresponding to amino acid residues 166-180 of human GPR84
-
亚型
- IgG
-
-
anti-G Protein-Coupled Receptor 84 (GPR84) (AA 21-120) antibody
GPR84 适用: 人, 小鼠, 兔 WB, ELISA, FACS, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 84 (GPR84) (Cytoplasmic Domain) antibodyGPR84 适用: 人 ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 84 (GPR84) (AA 208-316) antibodyGPR84 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5C3 unconjugated
anti-G Protein-Coupled Receptor 84 (GPR84) (AA 166-180), (Extracellular) antibodyGPR84 适用: 人 WB, FACS, IHC, LCI, IF 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 84 (GPR84) (Transmembrane Domain) antibodyGPR84 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 84 (GPR84) (Extracellular Domain) antibodyGPR84 适用: 人, 马, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 84 (GPR84) (N-Term) antibodyGPR84 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 84 (GPR84) (AA 1-100) antibodyGPR84 适用: 小鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 84 (GPR84) (AA 202-320) antibodyGPR84 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 84 (GPR84) (AA 208-316) antibodyGPR84 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
-
-
应用备注
-
Antigen preadsorption control: 1 μg peptide per 1 μg antibody
Application Dilutions Immunohistochemistry paraffin embedded sections ihc: N/A
Application Dilutions Western blot wb: N/A
-
说明
-
Negative Control: (ABIN7582046)
Blocking Peptide: (ABIN7235454)
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- 50 μL double distilled water (DDW).
-
浓度
- 1 mg/mL
-
缓冲液
- PBS pH 7.4, 1 % BSA with 0.05 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
-
-
- GPR84 (G Protein-Coupled Receptor 84 (GPR84))
-
别名
- GPR84
-
背景
-
G-protein coupled receptor 84, Inflammation-related G-protein coupled receptor EX33,GPR84 is an orphan G-protein coupled receptor (GPCR) activated by micromolar concentrations of medium-chain fatty acids (MCFAs). MCFAs that activate GPR84 are usually with carbon chain lengths of 9-14, which couples primarily to a pertussis toxin (PTX)-sensitive Gi/o pathway. The most potent agonists of GPR84 includes decanoic acid, undecanoic acid and lauric acid. GPR84 demonstrates an important role in inflammation, immunity, and cancer1-3.GPR84 is predominantly expressed in immune system-related tissues and cells, such as bone marrow, spleen, lung, lymph nodes and brain microglia, T-cells, macrophages and glial cells. Its expression is also detected in adipocytes.Studies have shown that GPR84 activation in murine macrophage-like cell line results in high levels of LPS-stimulated IL-12 p40 production. In addition, GPR84 knockout mice display increased Th2 cytokine production1-3.
Alternative names: G-protein coupled receptor 84, Inflammation-related G-protein coupled receptor EX33 -
基因ID
- 53831
-
NCBI登录号
- NM_020370
-
UniProt
- Q9NQS5
抗原
-
