GPR84 抗体 (2nd Extracellular Loop)
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Quick Overview for GPR84 抗体 (2nd Extracellular Loop) (ABIN7043175)
抗原
See all GPR84 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- 2nd Extracellular Loop, AA 166-180
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原理
- A Rabbit Polyclonal Antibody to GPR84
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Human - 14,15 amino acid residues identical, mouse,rat - 13
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产品特性
- Anti-GPR84 (extracellular) Antibody (ABIN7043175, ABIN7044443 and ABIN7044444) is a highly specific antibody directed against an epitope of the human protein. The antibody can be used in western blot, immunohistochemistry, and live cell flow cytometry applications. It has been designed to recognize GPR84 from human, rat, and mouse samples.
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纯化方法
- Affinity purified on immobilized antigen.
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免疫原
- CT(S)SFDRIRGRPYTT, corresponding to amino acid residues 166-180 of human GPR84
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亚型
- IgG
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anti-G Protein-Coupled Receptor 84 (GPR84) (AA 21-120) antibody
GPR84 适用: 人, 小鼠, 兔 WB, ELISA, FACS, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 84 (GPR84) (AA 208-316) antibodyGPR84 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5C3 unconjugated
anti-G Protein-Coupled Receptor 84 (GPR84) (Cytoplasmic Domain) antibodyGPR84 适用: 人 ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 84 (GPR84) (N-Term) antibodyGPR84 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 84 (GPR84) (Extracellular Domain) antibodyGPR84 适用: 人, 马, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 84 (GPR84) (Transmembrane Domain) antibodyGPR84 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 84 (GPR84) (2nd Extracellular Loop), (AA 166-180) antibody (PE)GPR84 适用: 人 FACS, LCI 宿主: 兔 Polyclonal PE
anti-G Protein-Coupled Receptor 84 (GPR84) (AA 1-100) antibodyGPR84 适用: 小鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 84 (GPR84) (AA 208-316) antibodyGPR84 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 84 (GPR84) antibodyGPR84 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: 1:200
FC: 2.5 μg per reaction
ICC: The optimal concentration should be determined by the user
IHC: 1:200
IP: The optimal concentration should be determined by the user
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说明
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Cited Application: IP
Negative Control: (ABIN7235454)
Blocking Peptide: (ABIN7235454)
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- 25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.
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浓度
- 0.8 mg/mL
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缓冲液
- PBS pH 7.4, 1 % BSA with 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
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- GPR84 (G Protein-Coupled Receptor 84 (GPR84))
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别名
- GPR84
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背景
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Synonyms: G-protein coupled receptor 84, Inflammation-related G-protein coupled receptor EX33
Description: GPR84 is an orphan G-protein coupled receptor (GPCR) activated by micromolar concentrations of medium-chain fatty acids (MCFAs). MCFAs that activate GPR84 are usually with carbon chain lengths of 9-14, which couples primarily to a pertussis toxin (PTX)-sensitive Gi/o pathway. The most potent agonists of GPR84 includes decanoic acid, undecanoic acid and lauric acid. GPR84 demonstrates an important role in inflammation, immunity, and cancer1-3.GPR84 is predominantly expressed in immune system-related tissues and cells, such as bone marrow, spleen, lung, lymph nodes and brain microglia, T-cells, macrophages and glial cells. Its expression is also detected in adipocytes.Studies have shown that GPR84 activation in murine macrophage-like cell line results in high levels of LPS-stimulated IL-12 p40 production. In addition, GPR84 knockout mice display increased Th2 cytokine production1-3.
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基因ID
- 53831
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NCBI登录号
- NM_020370
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UniProt
- Q9NQS5
抗原
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