GABARAPL1 抗体 (C-Term)
Quick Overview for GABARAPL1 抗体 (C-Term) (ABIN7233060)
抗原
See all GABARAPL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-GABARAPL1 Rabbit Polyclonal Antibody
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特异性
- This antibody recognizes human GABARAPL1.
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交叉反应
- 人
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免疫原
- Synthetic peptide corresponding to the C-terminus of human GABARAPL1
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anti-GABA(A) Receptor-Associated Protein Like 1 (GABARAPL1) (AA 1-117) antibody
GABARAPL1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-GABA(A) Receptor-Associated Protein Like 1 (GABARAPL1) (N-Term) antibodyGABARAPL1 适用: 人, 大鼠, 小鼠, 犬, 豚鼠, 马, 兔, Cow, Pig, Hamster, 猴, 小鸡, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-GABA(A) Receptor-Associated Protein Like 1 (GABARAPL1) (AA 1-117) antibodyGABARAPL1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-GABA(A) Receptor-Associated Protein Like 1 (GABARAPL1) antibodyGABARAPL1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB22950 unconjugated
anti-GABA(A) Receptor-Associated Protein Like 1 (GABARAPL1) (AA 1-117) antibodyGABARAPL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-GABA(A) Receptor-Associated Protein Like 1 (GABARAPL1) (AA 31-80) antibodyGABARAPL1 适用: 人, 大鼠, 小鼠, 犬, 豚鼠, 马, 兔, Cow, Pig, Hamster, 猴, 小鸡, 非洲爪蟾, Bat, Drosophila melanogaster, Insect WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-GABA(A) Receptor-Associated Protein Like 1 (GABARAPL1) (AA 35-84) antibodyGABARAPL1 适用: 人, 大鼠, 小鼠, 犬, 豚鼠, 马, 兔, Cow, Pig, Hamster, 猴, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-GABA(A) Receptor-Associated Protein Like 1 (GABARAPL1) antibodyGABARAPL1 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-GABA(A) Receptor-Associated Protein Like 1 (GABARAPL1) (Middle Region) antibodyGABARAPL1 适用: 人, 大鼠, 小鼠, 犬, 豚鼠, 马, 兔, Cow, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunoblotting: use at dilution of 1:1,000. A band of ~14-16 kDa is detected.
Immunofluorescence: use at dilution of 1:100
These are recommended working dilutions.
Endusers should determine optimal dilutions for their applications. -
限制
- 仅限研究用
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状态
- Liquid
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溶解方式
- Dilute in PBS or medium that is identical to that used in the assay system.
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH 7.4, 50 % glycerol, 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- This antibody is stable for at least one (1) year at -20°C.
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- GABARAPL1 (GABA(A) Receptor-Associated Protein Like 1 (GABARAPL1))
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别名
- GABARAPL1
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背景
- γ-aminobutyric acid receptor-associated protein-like 1,Ubiquitin-like modifier that increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracellular trafficking of the receptor (PubMed:16431922). Involved in formation of autophagosomal vacuoles (PubMed:20404487). While LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (PubMed:20404487). Through its interaction with the reticulophagy receptor TEX264, participates in the remodeling of subdomains of the endoplasmic reticulum into autophagosomes upon nutrient stress, which then fuse with lysosomes for endoplasmic reticulum turnover (PubMed:31006538, PubMed:31006537). {PubMed:16431922, PubMed:20404487, PubMed:31006537, PubMed:31006538}.,GABARAP, GABARAPL1 and GABARAPL2 genes are differentially expressed in normal and pathological tissues. The GABARAP gene is highly expressed in endocrine tissues while the GABARAPL1 gene is predominantly expressed in the central nervous system, but they both are underexpressed in a large variety of cancer cell lines. However, the analysis of GABARAPL1 expression in a cohort of 256 breast adenocarcinoma revealed that a low GABARAPL1 expression was correlated with a high risk of metastasis, in particular for lymph node-positive patients.,Cytoplasmic vesicle, autophagosome, Cytoplasmic vesicle membrane, Cytoplasm, cytoskeleton, Endoplasmic reticulum, Golgi apparatus,Early estrogen-regulated protein, GABA(A receptor-associated protein-like 1, Glandular epithelial cell protein 1, GEC-1
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UniProt
- Q9H0R8
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途径
- Autophagy
抗原
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