GABRD 抗体 (AA 15-34)
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Quick Overview for GABRD 抗体 (AA 15-34) (ABIN7233022)
抗原
See all GABRD 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 15-34
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原理
- Anti-δ GABA-A Receptor Mouse Monoclonal Antibody
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特异性
- This antibody recognizes mouse and rat Delta GABA-A receptor.
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交叉反应
- 小鼠, 大鼠
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纯化方法
- Purified by Protein G affinity chromatography.
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免疫原
- Synthetic peptide corresponding to aa 15-34 of rat Delta GABA-A receptor (accession no. P18506).
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亚型
- IgG2a
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应用备注
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Immunoblotting: use at 1-10 μg/mL. A band of ~55 kDa is detected.Immunohistochemistry and
Immunocytochemistry: use at 0.1-1 μg/mL
Immunofluorescence: use at 1-10 μg/mL
These are recommended concentrations. User should determine optimal concentrations for their application.
Positive control: Rat brain. -
限制
- 仅限研究用
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状态
- Liquid
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溶解方式
- Dilute in PBS or medium that is identical to that used in the assay system.
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浓度
- Lot specific
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缓冲液
- PBS, pH 7.4, 50 % glycerol, 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- This antibody is stable for at least one (1) year at -20°C.
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- GABRD (GABA A Receptor delta (GABRD))
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别名
- Gabrd
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背景
- γ-aminobutyric acid receptor subunit δ,GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.,GABA is the major inhibitory neuro- transmitter in the vertebrate brain. GABA receptors consist of five subunits that form a chloride ion channel. Subunit families alpha, beta, g, and delta have been studied extensively, e€ and epsilon have been identified recently. Studies of recombinant GABA receptors have shown that individual subunits and their subtypes confer different sensitivities to GABA receptor modulators. Subunit subtypes are differentially expressed throughout development and in different CNS regions, reducing the total number of possible isoforms that can be formed in different brain regions and in individual cells.,Cell junction, synapse, postsynaptic cell membrane, Multi-pass membrane protein. Cell membrane, Multi-pass membrane protein.,GABA(A receptor subunit δ
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UniProt
- P18506
抗原
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