CD57 抗体
Quick Overview for CD57 抗体 (ABIN7232911)
抗原
See all CD57 (B3GAT1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-CD57 Mouse Monoclonal Antibody
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特异性
- Human CD57. Reactivity with other species has not been investigated.
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交叉反应
- 人
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免疫原
- Recombinant human CD57.
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亚型
- IgG1
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anti-beta-1,3-Glucuronyltransferase 1 (Glucuronosyltransferase P) (B3GAT1) antibody (PE)
B3GAT1 适用: 人 FACS 宿主: 小鼠 Monoclonal TB01 PE
anti-beta-1,3-Glucuronyltransferase 1 (Glucuronosyltransferase P) (B3GAT1) (AA 193-334) antibodyB3GAT1 适用: 人 FACS, WB, ELISA 宿主: 小鼠 Monoclonal 3B8B10 unconjugated
anti-beta-1,3-Glucuronyltransferase 1 (Glucuronosyltransferase P) (B3GAT1) (AA 35-191) antibodyB3GAT1 适用: 人, 小鼠, 大鼠, 猴 FACS, WB, ELISA 宿主: 小鼠 Monoclonal 3F6D6 unconjugated
anti-beta-1,3-Glucuronyltransferase 1 (Glucuronosyltransferase P) (B3GAT1) (AA 28-334) antibodyB3GAT1 适用: 人 FACS, IHC, ELISA 宿主: 小鼠 Monoclonal 1A4F10 unconjugated
anti-beta-1,3-Glucuronyltransferase 1 (Glucuronosyltransferase P) (B3GAT1) antibody (APC)B3GAT1 适用: 人 FACS 宿主: 小鼠 Monoclonal TB01 APC
anti-beta-1,3-Glucuronyltransferase 1 (Glucuronosyltransferase P) (B3GAT1) (AA 21-120) antibodyB3GAT1 适用: 人, 小鼠, 大鼠 FACS, WB, IHC (p), ELISA, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-beta-1,3-Glucuronyltransferase 1 (Glucuronosyltransferase P) (B3GAT1) antibodyB3GAT1 适用: 人 FACS, WB, IHC (p), ICC, IHC (fro) 宿主: 小鼠 Monoclonal TB01 unconjugated
anti-beta-1,3-Glucuronyltransferase 1 (Glucuronosyltransferase P) (B3GAT1) antibody (Biotin)B3GAT1 适用: 人 FACS, IHC, IP 宿主: 小鼠 Monoclonal NK-1 Biotin
anti-beta-1,3-Glucuronyltransferase 1 (Glucuronosyltransferase P) (B3GAT1) antibody (FITC)B3GAT1 适用: 人 FACS, IHC 宿主: 小鼠 Monoclonal NK-1 FITC
anti-beta-1,3-Glucuronyltransferase 1 (Glucuronosyltransferase P) (B3GAT1) antibody (SPRD)B3GAT1 适用: 人 FACS, IHC 宿主: 小鼠 Monoclonal NK-1 SPRD
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应用备注
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Immunohistochemistry: use at a dilution of 1:100-1:200 on formalin-fixed, paraffin-embedded samples after heat-induced epitope retrieval at pH 9 for 10-30 minutes. -
限制
- 仅限研究用
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状态
- Liquid
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溶解方式
- Dilute in PBS or medium that is identical to that used in the assay system.
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浓度
- Lot specific
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缓冲液
- Tris buffer, pH 7.3-7.7, 1 % BSA, 0.1 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze.
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- CD57 (B3GAT1) (beta-1,3-Glucuronyltransferase 1 (Glucuronosyltransferase P) (B3GAT1))
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别名
- B3GAT1
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背景
- Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1,Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group. {UniProtKB:O35789}.,It was originally believed that CD57 (cluster of differentiation 57) was uniquely expressed on natural killer (NK) cells, but further research showed that CD57 was expressed only on a subset of functionally distinct NK cells. CD57 was subsequently identified on CD8+ T cells as well as on cells of neural crest origin. In neural cells, the CD57 epitope is predominantly restricted to adhesion molecules. CD57 has been utilized as a marker for tumors of neuroendocrine origin including pheochromocytomas, paragangliomas, carcinoid tumors, medulloblastomas, neuromas, neurofibromas, schwannomas, and granular cell tumors. Expression of CD57 can be used to distinguish nodular lymphocyte-predominant Hodgkin's lymphoma from T-cell/histiocyte-rich large B-cell lymphoma, nodular sclerosis, Hodgkin's disease, and follicular lymphoma.,[Isoform 1]: Golgi apparatus membrane, Secreted, Endoplasmic reticulum membrane, Secreted,EC 2.4.1.135, Beta-1,3-glucuronyltransferase 1, Glucuronosyltransferase P, GlcAT-P, UDP-GlcUA:glycoprotein beta-1,3-glucuronyltransferase, GlcUAT-P
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UniProt
- Q9P2W7
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途径
- Glycosaminoglycan Metabolic Process
抗原
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