Glutathione Reductase 抗体 (AA 44-522)
Quick Overview for Glutathione Reductase 抗体 (AA 44-522) (ABIN7232834)
抗原
See all Glutathione Reductase (GSR) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 44-522
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原理
- Anti-Glutathione Reductase Mouse Monoclonal Antibody
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特异性
- These antibodies recognize human glutathione reductase. They do not cross-react with yeast glutathione reductase.
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交叉反应
- 人
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免疫原
- Recombinant human glutathione reductase purified from E. coli expressing the human glutathione reductase gene (aa 44-522).
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亚型
- IgG1
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应用备注
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ELISA: Titration of glutathione reductase MAbs with glutathione reductase at 3 μg/mL on the wells.ELISA Pairs: Both of these antibodies function as capture and detection antibodies at 1 μg/mL.
Immunoblotting: use at 0.5-1.0 μg/mL. A band of ~57 kDa is detected.
These are recommended concentrations.
Endusers should determine optimal concentrations for their applications. -
限制
- 仅限研究用
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状态
- Liquid
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溶解方式
- Dilute in PBS or medium that is identical to that used in the assay system.
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浓度
- Lot specific
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缓冲液
- PBS, pH 7.4
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储存条件
- -20 °C
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储存方法
- These antibodies are stable for at least one (1) year at -20°C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles.
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- Glutathione Reductase (GSR)
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别名
- GSR
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背景
- Glutathione reductase, mitochondrial,Maintains high levels of reduced glutathione in the cytosol.,Glutathione reductase, also known as glutathione-disulfide reductase, is an enzyme that in humans is encoded by the GSR gene. Glutathione reductase catalyzes the reduction of glutathione disulfide to the sulfhydryl form glutathione (GSH), which is a critical molecule in resisting oxidative stress and maintaining the reducing environment of the cell. The importance of the glutathione pathway and enzymes that affect it is gaining an increased level of attention. Although glutathione reductase has been an attractive target for many pharmaceuticals, there have been no successful glutathione reductase related therapeutic compounds created to date.,[Isoform Mitochondrial]: Mitochondrion., [Isoform Cytoplasmic]: Cytoplasm.,GR, GRase, EC 1.8.1.7
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NCBI登录号
- NP_000628
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UniProt
- P00390
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途径
- Thyroid Hormone Synthesis, Cell RedoxHomeostasis
抗原
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