ENPP2 抗体 (AA 131-230) (Biotin)
Quick Overview for ENPP2 抗体 (AA 131-230) (Biotin) (ABIN716788)
抗原
See all ENPP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 131-230
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交叉反应
- 小鼠
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预测反应
- Human,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human ENPP2
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亚型
- IgG
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应用备注
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IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- ENPP2 (Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2))
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别名
- Enpp2
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背景
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Synonyms: ATX, Autotaxin,E NPP 2, E-NPP 2, Ectonucleotide pyrophosphatase/phosphodiesterase 2, Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, Enpp2, ENPP2_HUMAN, Extracellular lysophospholipase D, LysoPLD, PDNP2.
Background: Hydrolyzes lysophospholipids to produce lysophosphatidic acid (LPA) in extracellular fluids. Major substrate is lysophosphatidylcholine. Also can act on sphingosylphosphphorylcholine producing sphingosine-1-phosphate, a modulator of cell motility. Can hydrolyze, in vitro, bis-pNPP, to some extent pNP-TMP, and barely ATP. Involved in several motility-related processes such as angiogenesis and neurite outgrowth. Acts as an angiogenic factor by stimulating migration of smooth muscle cells and microtubule formation. Stimulates migration of melanoma cells, probably via a pertussis toxin-sensitive G protein. May have a role in induction of parturition. Possible involvement in cell proliferation and adipose tissue development. Tumor cell motility-stimulating factor.
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基因ID
- 5168
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UniProt
- Q13822
抗原
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