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XIAP 抗体 (pSer87)

This anti-XIAP antibody is a 兔 多克隆 antibody detecting XIAP in WB, ELISA 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7221588
发货至: 中国

Quick Overview for XIAP 抗体 (pSer87) (ABIN7221588)

抗原

See all XIAP 抗体
XIAP (X-Linked Inhibitor of Apoptosis (XIAP))

适用

  • 82
  • 44
  • 30
  • 3
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 73
  • 13
  • 1

克隆类型

  • 73
  • 12
多克隆

标记

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  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This XIAP antibody is un-conjugated

应用范围

  • 72
  • 35
  • 26
  • 17
  • 16
  • 13
  • 13
  • 13
  • 9
  • 6
  • 3
  • 2
  • 2
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 16
    • 12
    • 8
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer87

    原理

    XIAP (phospho Ser87) Polyclonal Antibody

    特异性

    Phospho-XIAP (S87) Polyclonal Antibody detects endogenous levels of XIAP protein only when phosphorylated at S87.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human XIAP Phospho-Ser87

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    XIAP (X-Linked Inhibitor of Apoptosis (XIAP))

    别名

    XIAP

    背景

    Rabbit Anti-XIAP (phospho Ser87) Polyclonal Antibody,XIAP, API3, BIRC4, IAP3, E3 ubiquitin-protein ligase XIAP, Baculoviral IAP repeat-containing protein 4, IAP-like protein, ILP, hILP, Inhibitor of apoptosis protein 3, IAP-3, hIAP-3, hIAP3, X-linked inhibitor of apoptosis protein, X-linked I,XIAP encodes X-linked inhibitor of apoptosis that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.,E3 ubiquitin-protein ligase XIAP

    分子量

    observerd band 57kDa

    基因ID

    331

    UniProt

    P98170

    途径

    Apoptosis, Caspase Cascade in Apoptosis, Transition Metal Ion Homeostasis
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