XIAP 抗体
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北京 101111
Quick Overview for XIAP 抗体 (ABIN7217512)
抗原
See all XIAP 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- XIAP Polyclonal Antibody
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特异性
- XIAP Polyclonal Antibody detects endogenous levels of XIAP protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human XIAP around the non-phosphorylation site of S87
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亚型
- IgG
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anti-X-Linked Inhibitor of Apoptosis (XIAP) (pSer87) antibody
XIAP 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-X-Linked Inhibitor of Apoptosis (XIAP) (C-Term) antibodyKO Validated XIAP 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-X-Linked Inhibitor of Apoptosis (XIAP) (AA 201-330) antibodyXIAP 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-X-Linked Inhibitor of Apoptosis (XIAP) (AA 1-497) antibodyXIAP 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-X-Linked Inhibitor of Apoptosis (XIAP) (AA 1-497) antibodyXIAP 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-X-Linked Inhibitor of Apoptosis (XIAP) (AA 1-497) antibodyXIAP 适用: 人 WB, IF, PLA 宿主: 兔 Polyclonal unconjugated
anti-X-Linked Inhibitor of Apoptosis (XIAP) (AA 51-150) antibodyXIAP 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 1F4 unconjugated
anti-X-Linked Inhibitor of Apoptosis (XIAP) (AA 1-268) antibodyXIAP 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 4C12G10 unconjugated
anti-X-Linked Inhibitor of Apoptosis (XIAP) (AA 1-30) antibodyXIAP 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-X-Linked Inhibitor of Apoptosis (XIAP) (AA 1-200) antibodyXIAP 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- XIAP (X-Linked Inhibitor of Apoptosis (XIAP))
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别名
- XIAP
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背景
- Rabbit Anti-XIAP Polyclonal Antibody,XIAP, API3, BIRC4, IAP3, E3 ubiquitin-protein ligase XIAP, Baculoviral IAP repeat-containing protein 4, IAP-like protein, ILP, hILP, Inhibitor of apoptosis protein 3, IAP-3, hIAP-3, hIAP3, X-linked inhibitor of apoptosis protein, X-linked I,XIAP encodes E3 ubiquitin-protein ligase XIAP that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.,E3 ubiquitin-protein ligase XIAP
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分子量
- observerd band 57kDa
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基因ID
- 331
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UniProt
- P98170
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途径
- Apoptosis, Caspase Cascade in Apoptosis, Transition Metal Ion Homeostasis
抗原
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