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WISP3 抗体 (AA 1-50)

The 兔 多克隆 anti-WISP3 antibody (ABIN7227052) specifically detects WISP3 in WB 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7227052
发货至: 中国
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Quick Overview for WISP3 抗体 (AA 1-50) (ABIN7227052)

抗原

See all WISP3 抗体
WISP3 (Wnt1 Inducible Signaling Pathway Protein 3 (WISP3))

适用

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宿主

  • 39
  • 1

克隆类型

  • 40
多克隆

标记

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This WISP3 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

    • 15
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    • 1
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    AA 1-50

    原理

    WISP-3 Polyclonal Antibody

    特异性

    The antibody detects endogenous WISP-3.

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthetic peptide from human protein at AA range: 1-50

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    WISP3 (Wnt1 Inducible Signaling Pathway Protein 3 (WISP3))

    别名

    WISP-3

    背景

    Rabbit Anti-WISP-3 Polyclonal Antibody,WNT1-inducible-signaling pathway protein 3, WISP-3, CCN family member 6,WISP3 (WNT1 inducible signaling pathway protein 3) encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. WISP3 is overexpressed in colon tumors. It may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Mutations of WISP3 are associated with progressive pseudorheumatoid dysplasia, an autosomal recessive skeletal disorder, indicating that the gene is essential for normal postnatal skeletal growth and cartilage homeostasis. Multiple transcript variants encoding different isoforms have been found for WISP3.,WNT1-inducible-signaling pathway protein 3 (WISP-3) (CCN family member 6)

    分子量

    observerd band 55kDa

    基因ID

    8838

    UniProt

    O95389

    途径

    WNT signaling, Growth Factor Binding
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